Cannabis : What You Need To Know

Cannabis Is In Your DNA

Science Explains How Cannabis Kills Cancer Cells

Cannabis is an annual, dioecious, flowering herb. The leaves are palmatelycompound or digitate, with serrate leaflets. The first pair of leaves usually have a single leaflet, the number gradually increasing up to a maximum of about thirteen leaflets per leaf (usually seven or nine), depending on variety and growing conditions. At the top of a flowering plant, this number again diminishes to a single leaflet per leaf. The lower leaf pairs usually occur in an opposite leafarrangement and the upper leaf pairs in an alternate arrangement on the main stem of a mature plant.

The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). As is common in serrated leaves, each serration has a central vein extending to its tip. However, the serration vein originates from lower down the central vein of the leaflet, typically opposite to the position of, not the first notch down, but the next notch. This means that on its way from the midrib of the leaflet to the point of the serration, the vein serving the tip of the serration passes close by the intervening notch. Sometimes the vein will actually pass tangent to the notch, but often it will pass by at a small distance, and when that happens a spur vein (occasionally a pair of such spur veins) branches off and joins the leaf margin at the deepest point of the notch. This venation pattern varies slightly among varieties, but in general it enables one to tell Cannabis leaves from superficially similar leaves without difficulty and without special equipment. Tiny samples of Cannabis plants also can be identified with precision by microscopic examination of leaf cells and similar features, but that requires special expertise and equipment.

The plant is believed to have originated in the mountainous regions northwest of the Himalayas. It is also known as hemp, although this term is often used to refer only to varieties of Cannabis cultivated for non-drug use.

Wikipedia Highlights

(Dr.William Courtney)

The sites of action of Phytocannabinoids

ECS modulates cellular function, the more one knows about the range of cell structure and function the better one can conceive of phytocannabinoid influenced cellular modulation. Up and down regulation of the cell specific physiologic and pathophysiologic function.

The Endogenous Cannabinoid System

A group of neuromodulatory lipids and their receptors that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis.

Cannabinoid Receptors

The Cannabinoid Receptors are one of several sites of actions of the Phytocannabinoids.

Enzymes

Phytocannabinoids also have direct action of enzymes & channels. This article covers the generic principals.

Overview of cannabis limited to psychoactive uses

I hope if you are at this level at Cannabis International you are interested in anti-oxidant anti-inflammatory, anti-neoplastic, or other uses ideally in a preventive or therapeutic mode, more accurately in a phrase, developing recognition of cannabis as a ‘dietary essential’. Other than the initial comments, an incredible series of links.

Medical Cannabis

More on point, this medical cannabis page does not emphasize the cannabinoid acids that act at GPR55, affectionately known as the Orphan Receptor. There is no doubt it deserves to be CB3, the Phytocannabinoid Receptor, where the delicate cannabinoid acids act as an antagonist producing their potent anti-inflammatory effects.

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